Are you using an ATA66 cable? The 106S should be set as master and you <b>must</b> use an ATA66 cable if your controller is ATA66 or higher as the drive is spec'ed as UDMA66 (the only one in existance, AFAIK). I had problems with mine when I moved to my ATA100 board and tried to use my old ATA33 cable - problems with detection and boot - especially with another drive on the channel. Good news is: when you get it to work with your CD-RW on the same channel, you can pretty much ignore the warnings your CD writer software (nero in particular) will throw at you about writing on the fly from disk to disk on the same channel - ATA66 makes it so much more efficient at reading and writing that my setup doesn't even use the buffer under-run protection. I don't know all the details of why, but it certainly works. I LOVE my 106S! (and for all of the elementary school kids out there - I'm already married, so I can't...).
I thought a thought, but the thought I thought wasn't the thought I thought I had thought.