if you have a standard case with casefans then normal airflow will be sufficient.
given that your casetemp is 45C i would have to say one of the following things.
A. you live in a very hot climate, and thus it might be a good idea getting a HDD cooler or put the HDD behind the front casefan (assuming there is one)
B. if the room temp is cool, yet your casetemp 45C, i would seriously reccomend better case cooling.
C. if the case feels cool, then the temp is being missreported.
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