Well, I've heard Skyrim MAY contain a few bugs. I'm thinking of petitioning to have the name changed to "Bugger-Rim" but the connotations aren't great.
I actually bought the game on sale with the intention of waiting for the amount of bugs to drop before playing.
My big pet peeve is the way characters and creatures seem to slide around when standing still like they are on ice. It kind of removes me from the immersion.