As mentioned, there can be issues with getting rid of your PageFile entirely, but since you have so much RAM, perhaps consider making a small 1GB RAMDisk and putting the page file on there?
I have 16GB, and I make my RAMDisk 4GB so it holds the PageFile, Windows temp, Firefox temp, and other temp files in the speediest possible storage I can use.
That's a good idea but some programs require pagefile to be on C:\. I've run across a few games that expect a pagefile on C:\ (MW3, BF3) and cause BSOD if it's not - ie; "PAGE_FAULT_IN_NON-PAGED_AREA". Even went so far to create pagefile on a different drive to no avail. Only solution was to create a small 2GB pagefile.