Big Loss in video quality with DVI/VGA converter on an HDTV?

I'm looking to build a new system to hook up to my HDTV, and I was noticing that most of the video cards I want all have only DVI and S-Video connectors. My Vizio 42" HDTV only has HDMI, S-video, VGA and component inputs (along with standard analog) and I'm wondering if using the DVI to VGA converters that come with these cards is going to significantly degrade the image quality. Right now my current PC (w/ a Nvidia 6600) is hooked up via VGA, and it looks pretty clean so I'd be satisfied if I got the same result. (Which is why S-video is out of the question).

If there was a way to output everything through HDMI that'd be even better.

Thanks for any help.

Well that's certainly a solution. Actually that would be fantastic. Thanks!