Depending on the size and resolution of your TV (i.e., 45" and 1080P), you might find it more comfortable at least 4-6 ft. away from your eyes as opposed to on your desk, which could mean a wall-mount kit is necessary. Any closer and you might notice the individual pixels.
I use a Pioneer plasma 50" but only as a 2nd monitor, and it is mounted on the wall about 4 ft away. Great for that immersive gaming experience, but I wouldn't want to work on a wordprocessing document or spreadsheet for any length of time using it .
Alternatively several companies make monitors that include a tuner, such as Samsung's Touch of Color series which I have seen in the store and think is pretty nice-looking.