Without laptop hard drive, can i connect to the desktop HD from laptop

Is my laptop(compaq presario c700) work if i remove its hard drive and connect to desktop hard drive through 'usb to hard drive adapter'?
If it works, can i use all the applications(softwares) of my desktop hard drive without problems?
please reply me soon, waiting for your help.
Thanks in advance for help..
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More about without laptop hard drive connect desktop laptop
  1. Chances are that you can't boot from a USB harddrive with your laptop. Why do you want to do this anyway?
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