The difference is speed. A 2 TB drive is really, really slow.
BUT, there is hope, you can fix that.
The operating system should be installed on a small fast drive. (like 70 GB, example)
The 2 TB drive is used to store files, such as, pictures, documents, music, video...
But, do not mix the operating system with all those files. Keep them on separate drives.
Set the bios to boot the small OS drive first.
Now the system will go way faster...