There are a few things you can try without any other information:
I would recommend running either MalwareBytes Anti-Malware
or Super Anti-Spyware
or even both to see if something has infected the system.
It's time you take a look at everything running and starting up when your computer does.
I would recommend using Autoruns
Not sure what all those things are? Go to HERE
for help with identifying those pesky startup items.