So far I've only noticed this problem with The Witcher, Dragon Age: Origins, STALKER and to a lesser extent Risen.
When the game is in full screen mode the screen flickers when any quick action happens on screen, such as moving the mouse to look around, characters fighting in cutscenes, things like lightning that flash across the screen or even the logo popping up on start up. It's almost like a stutter, but only on part of the screen.
If however I change to windowed mode, even in the same resolution, the flicker goes away.
I tried uninstalling and reinstalling the video card drivers multiple times, no change.
I have an HP Envy 17 laptop running Windows 7 64-bit with a i7 720, 6GB of RAM and a Mobility Radeon HD 5850.