Probably not, if you are running W7 (64bit with that much memory), it may well slow the system down, the only way that I know of to speed the boot up, is with a SSD, something about 150G to 200G, and install only windows on this drive and the really necessary boot programs, Antivirus, Net, Video and Sound (at boot Win reads all the files listed in the MBR, with 1 TB that can take a while) install all the other Apps on the Spinpoint, using a smaller drive for boot can speed the bootup considerably, I use a 250G for boot, 500G for apps and Games, 1TB and a 1.5TB for Archiving(ESATA) so I can turn them on and off