I've got a problem with bioshock (for PC). There seems to be about a 70-80% chance of a crash when picking up plasmids/tonics, or any other vial that gives abilities. I've had it crash once when harvesting a sister, but i think that time it may have been heat related (forgot to turn up fans after starting the game)
Basically is, i'll pick it up, and that brief second that the game pauses before the pop-up shows up is when it mostly freezes. Sometimes it'll give my PC a hard lock up, other times it'll boot me to desktop with windows saying there was a problem with my graphics drivers.
weird, have you tried lowering the settings, Its unlikely to make a difference but it might, you should certainly try reinstalling the game you could also make certain that you don't have any old drivers or anything clogging up your system
Welcome to the club! Stop wasting your time on this, as you'll never be able to fix it. The game code is just a mess. Even the X360 version has all kinds of problems. Go to the forums section of this website so you can marvel at all the problems this game causes.
luckily for you i have a solution for yo
i have a similar system to yours:
vista x64 ultimate...
I also had the EXACT problem you have...the simple solution is to disable sli for as long as you play bioshock....and i mean disable sli...not selecting single-gpu mode in the bioshock sli profile....since we quite have the same system i think this will fix your problem...