If you're an elcrical-engeneer or such and have access to a four layer PC-board factory with a wide bulk parts inventory and good credit, you night... if you order 5000 of them.
yet, you'll have to design your own MOBO. would cost you much less to buy a new board and you would get the resulting product of a dozen or more engeneer's work.
I used to work for a mobo manufacturer... couldn't resist replying to this one!