VCR sized HTPC / light gaming rig here I come. I hope asus creates one of these for FM2+ chipset / Kaveri APU. Intel's onboard video still does not offer enough performance for my liking.
The 16x PCIe while great in theory is effectively useless. Any cases made for this size board are as diminutive as possible, adding a 13" full height video card would require a standard ATX power supply, much greater airflow, and a much larger enclosure.
At that point, why would you stick an m-itx board in a m-atx case, just buy an matx board...