Just bandwidth. x4 has 4x the bandwidth as x1. And each generation gap doubles bandwidth. So let's say you have a PCIe 2.0 x8 card reader or whatever, Just an example by the way. You can plug that into a PCIe 2.0 x8, PCIe x16, PCIe 3.0 x4, PCIe 3.0 x8, or PCIe 3.0 x16 to provide it with the necessary bandwidth.