Gtx 650ti + Antec 620 watts modular psu.

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It's an 80+ and the 650ti only uses 110W max, so I see no problem. I'm not an expert on PSU's though, but an 80+ 620 watts should power a 650ti no problem. What are your other components? You need to make sure all of your components together don't use more than the 620 watts the PSU can take.