The other R9 280X cards have a TDP approaching 300W, but the Toxic reaches closer to the 375W it's specifically hardwired for. While it's impractical to think the card will run at 100% load 100% of the time, it leaves much less headroom than you think. It's specifically designed with two 8-pin PCIe connectors for a reason (375W total draw capability for the card itself). Assuming a conservative 320W per card, that comes to 640W total just for the two Toxic cards, leaving 110W for the rest of the system under load. 90W is taken by the CPU, not accounting for any system overclock, leaving 20W for the components.
He should be using an 850W PSU minimum with two Toxic cards if he doesn't want to stress the components and shorten their lifespan. 1000W would be ideal, especially if he intends any serious overclocking.