This is a monster indeed. Keeping with your needs, this is what I'd get for ~$5000.
PCPartPicker part list:
http://pcpartpicker.com/p/3hW1p
Price breakdown by merchant: http://pcpartpicker.com/p/3hW1p/by_merchant/
Benchmarks: http://pcpartpicker.com/p/3hW1p/benchmarks/
CPU: Intel Core i7-4930K 3.4GHz 6-Core Processor ($565.25 @ SuperBiiz)
CPU Cooler: Swiftech H320 55.0 CFM Liquid CPU Cooler ($169.99 @ NCIX US)
Motherboard: Gigabyte GA-X79-UP4 ATX LGA2011 Motherboard ($229.99 @ Micro Center)
Memory: Patriot Viper 3 32GB (4 x 8GB) DDR3-2133 Memory ($283.41 @ NCIX US)
Storage: Samsung 840 EVO 500GB 2.5" Solid State Disk ($251.99 @ Amazon)
Storage: Western Digital Red 3TB 3.5" 5400RPM Internal Hard Drive ($129.99 @ Amazon)
Storage: Western Digital Red 3TB 3.5" 5400RPM Internal Hard Drive ($129.99 @ Amazon)
Video Card: Gigabyte GeForce GTX 780 Ti 3GB Video Card (2-Way SLI) ($724.99 @ Amazon)
Video Card: Gigabyte GeForce GTX 780 Ti 3GB Video Card (2-Way SLI) ($724.99 @ Amazon)
Case: Corsair 750D ATX Full Tower Case ($149.99 @ NCIX US)
Power Supply: SeaSonic X Series 1250W 80+ Gold Certified Fully-Modular ATX Power Supply ($288.98 @ SuperBiiz)
Optical Drive: Asus BW-12B1ST/BLK/G/AS Blu-Ray/DVD/CD Writer ($66.99 @ Newegg)
Optical Drive: Asus BW-12B1ST/BLK/G/AS Blu-Ray/DVD/CD Writer ($66.99 @ Newegg)
Monitor: Asus PB278Q 27.0" Monitor ($549.99 @ Amazon)
Monitor: Asus PB278Q 27.0" Monitor ($549.99 @ Amazon)
Total: $4883.52
(Prices include shipping, taxes, and discounts when available.)
(Generated by PCPartPicker 2014-03-28 11:17 EDT-0400)