V-sync can have Input lag assiosiated with it, but iwas wondering it it has no effect if your using an Xbox 360 controller on a game that natively supports it like Titanfall or Call of Duty
V-sync's latency issues have nothing to do with your input device. It will still exist, regardless. However, when playing with a controller, latency is not as noticeable, as that type of input is not tied so closely to your hand movements.
Above is pretty true. Since the speed of your movement is consistent with a controller the lag isn't really all that noticeable, even if its horrible with a mouse.