(2x4GB + 2x2GB) in dual channel different mhz

[enj421]

Can i use this set in one channel http://www.newegg.com/Product/Product.aspx?Item=N82E16820231275&cm_re=4gb_ddr3_1333-_-20-231-275-_-Product
and this set in the other http://www.newegg.com/Product/Product.aspx?Item=N82E16820231445&cm_re=ddr3_1600-_-20-231-445-_-Product
Will the each run at there own speed or will it be limited to 1333mhz or not work properly at all.
i already have the two 2g sticks at 1333mhz. would it be best to upgrade to the 1600mhz or just get two more of the sticks i already have.

 

[Tradesman1]

A definite Maybe - if the set will play together at all, prob at most 1333/9 maybe 1600/9. Anythime you mix sets/packages of DRAM it can be and often is problematic, even more so when using sticks of different specs - am guessing prob could run 1333/9 and possible 1600/9 with a slight voltage adjustments to the DRAM and MC...would try the 1600 sticks in sots 1-3 from CPU and the 1333 sticks in 2-4