Which GPU are you using? Prior to 10series, I believe nVidia limited to 8bit to 'force' pro's to buy Quadros etc. I believe a driver revision opened this up a little while ago. AMD offerings supported 10bit.
Anyway, to the point: provided the card can do 10bit and the interface and display can, then the adapter shouldn't impact anything.
DP 1.4 can, HDMI 2.0 can, I assume your display can..... the adapter shouldn't play any factor IMO.
The fact you have a mDP intrigues me though.... which GPU are you using?