This is the problem of perfection. Just accept some non perfect settings and enjoy the beautiful games. Probably with the first 3 or 5 games you can't enjoy them, but doing it you will learn to accept it. Other than this, I don't know. Try to use recommended settings from ingame or friends/community. But if you really have fun with finding best settings, why not doing it, if you like?
Edit: @t53186, wrong and this was really not needed comment.
Btw, if you can start a webpage with listing of all of your findings and recommendations. Just an idea.