Can I upgrade my GPU on an OEM?

[roblox.gaming4k]

I want to get a GTX 1070 and a new power supply for my PC. I currently have a GTX 1050 Ti and want to increase my wattage. Would changing either of these affect my OEM OS? Will I have to reinstall it or will it be fine?

 

[kanewolf]

Neither of the things you reference will impact an OEM operating system.