Every motherboard uses specific drivers. I can't tell you exactly how much different for example Chipset is or any other driver- if it is the same manufacturer, you can try to compare the file names on your old drivers list with file names on the new motherboard drivers list. If it is different manufacturer, I would reinstall Windows and install new drivers. Register your Windows with your account. When reinstalling, you can try to add the same serial, but it may say that it was already used. You can use "I don't have it" option, install, then loig in to your Microsoft account and it may recognize you. Yeah... I am afraid it may want you to unregister your first computer- there was success with using phone support for registration. It considers it new system if you change 3 elements.