I also have the PG279Q. Had it for over a year now and it has never done anything like that. Is this a new monitor or did it just start happening out of the blue? Are you using the amphenol display port cable that should've came with the monitor? GPU drivers are installed? There is also a driver for that monitor you may want to try, doubtful it will solve that however.
https://www.asus.com/us/ROG-Republic-Of-Gamers/ROG-SWIFT-PG279Q/HelpDesk_Download/