37Penguins :
I'm upgrading my motherboard to a MSI B350 Pc Mate. I'm worried that some of my drivers will be corrupted when i upgrade it, or I will lose some stuff. Will this happen, and how can i prevent it?
Changing
from what?
Generally, with a new motherboard, a clean install is strongly recommended, often required.
There are 3 possible outcomes:
1. It boots up just fine
2. It fails completely
3. It boots up, but you're chasing issues for weeks.
The only "prevention" is "preparation" for that full wipe and reinstall.
Secondly:
For the OS activation, read and do this before you change any parts:
https://support.microsoft.com/en-us/help/20530/windows-10-reactivating-after-hardware-change...