‘200,000 living human neurons’ on a microchip demonstrated playing Doom — Cortical Labs CL1 video shows the gameplay and explains how the neurons learn the game

Cortical Labs CL1
(Image credit: Cortical Labs)

Australia’s Cortical Labs has demonstrated its 'body in a box' CL1 biological computer playing Doom. A video showing the Doom gameplay, and explaining the processes behind this feat was shared by the research and development team. In the video intro, it is claimed that “around 200,000 living human neurons on a microchip” were used to power the seminal FPS action.

Living Human Brain Cells Play DOOM on a CL1 - YouTube Living Human Brain Cells Play DOOM on a CL1 - YouTube
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Mark Tyson is a news editor at Tom's Hardware. He enjoys covering the full breadth of PC tech; from business and semiconductor design to products approaching the edge of reason.

  • -Fran-
    This is interesting, but I have to ponder: isn't the whole point of making machines not biological about removing the fragility (as much as possible) of humans? Did they quote a failure rate for their prototypes?

    I say this, because to my understanding neurons are very fragile in the human body (hence why whacking someone in the head is not a good thing). Humans compensate, somewhat, by having quite a lot of them: ~85000 million with a quick search.

    Still, it doesn't take away the amazingness of it. I look forward to the medical applications of this.

    Regards.
    Reply
  • Spuwho
    They aren't recreating the biological neurons physically, they are reproducing them digitally. So the "hit in the head" argument is not quite analogous. They are attempting to impress human engrams that are based on bio-neural pathways onto silicon. By playing Doom, they are baselining the capabilities of their work. Technically they could attempt to recreate any mammal since they all use bio-neural driven brain processing, but we haven't developed ways to test them because humans don't know how all mammals think. What is deduced, what is experiential, and what is instinctual.
    Reply
  • -Fran-
    Spuwho said:
    They aren't recreating the biological neurons physically, they are reproducing them digitally. So the "hit in the head" argument is not quite analogous. They are attempting to impress human engrams that are based on bio-neural pathways onto silicon. By playing Doom, they are baselining the capabilities of their work. Technically they could attempt to recreate any mammal since they all use bio-neural driven brain processing, but we haven't developed ways to test them because humans don't know how all mammals think. What is deduced, what is experiential, and what is instinctual.
    Thanks for the clarification. Very badly named tech then :D

    Regards.
    Reply
  • patriotpa
    Since when is it legal to play with human brain tissue?
    Reply
  • 80251
    Spuwho said:
    They aren't recreating the biological neurons physically, they are reproducing them digitally. So the "hit in the head" argument is not quite analogous. They are attempting to impress human engrams that are based on bio-neural pathways onto silicon. By playing Doom, they are baselining the capabilities of their work. Technically they could attempt to recreate any mammal since they all use bio-neural driven brain processing, but we haven't developed ways to test them because humans don't know how all mammals think. What is deduced, what is experiential, and what is instinctual.
    So they aren't "living neurons" at all, because they're not alive.

    I have to admit I was curious as to how they would keep biological cells alive in a silicon substrate.
    Reply
  • bit_user
    Spuwho said:
    They aren't recreating the biological neurons physically, they are reproducing them digitally.
    No, this is incorrect. The article is pretty explicit that these are biological neurons. If there was any doubt, the article links to a prior piece which explains more about the setup.
    https://www.tomshardware.com/tech-industry/worlds-first-body-in-a-box-biological-computer-uses-human-brain-cells-with-silicon-based-computing
    You can also click through the image carousel to see a few other pics:

    FWIW, I doubt the brain organoid is being fed raw pixel data. I think it must be preprocessed in some way. It's not nearly enough neurons to perform simple vision tasks.
    Reply
  • bit_user
    80251 said:
    So they aren't "living neurons" at all, because they're not alive.

    I have to admit I was curious as to how they would keep biological cells alive in a silicon substrate.
    Their website says "Real neurons are cultivated inside a nutrient rich solution, supplying them with everything they need to be healthy." !
    https://corticallabs.com/cl1.html
    Did it ever occur to you or @-Fran- to go back and check the article, when somebody (esp. with no sources or references) contradicts it?
    Reply
  • bit_user
    patriotpa said:
    Since when is it legal to play with human brain tissue?
    A human brain has about 90 billion neurons. This has 200k. That's almost a 6-order-of-magnitude difference!

    So, it's definitely not thinking. It's just on par with something like a simple insect.
    Reply
  • -Fran-
    bit_user said:
    Their website says "Real neurons are cultivated inside a nutrient rich solution, supplying them with everything they need to be healthy." !
    https://corticallabs.com/cl1.html
    Did it ever occur to you or @-Fran- to go back and check the article, when somebody (esp. with no sources or references) contradicts it?
    It did, but I'm lazy like that.

    Plus, I know you're around :P

    Regards.
    Reply
  • 80251
    Neurons can live for 90 years. I'd like to see proof that this biological device can do anything useful and for $35k they'll need some independent proof to convince me.
    Reply