PCPartPicker does overestimates, since it’s based on max TDP values for each component. Your system will never have every component at 100% usage.
Most of the power you system consumes is from the 12v rail, so what’s more important than the overall wattage is the delivery on the 12v line. It may only be 420w.
If your PSU has adequate protections, such as Over Current Protection or Over Power Protection, and is good quality, it shouldn’t damage components if your system pulls more than 450w.
However if you’re PSU lacks protections and/or low quality, it can damage parts.
What is your exact power supply and full system specs?